How does fasting makes difference for cancer cells?
The answer lies in how the body cells react to what they perceive as “starvation mode.” Valter Longo, associate professor of gerontology and biology at USC, explained the results of his 2009 study:
“In essence, these cells are waiting out the lean period, much like hibernating animals. But cancerous tumors respond differently to starvation; they do not stop growing, nor do they hibernate because their genetic pathways are stuck in an ‘on’ mode. Longo realized that the starvation response might differentiate healthy cells from cancer cells by their increased stress resistance and that healthy cells might withstand much more chemotherapy than cancer cells.”
Longo also reported that the studies are showing that fasting alone is enough to treat many types of cancer. Because the body’s healthy cells are in hibernation mode, the cancer cells try to find other ways to divide and proliferate, but without much success:
“The cell is, in fact, committing cellular suicide. What we’re seeing is that the cancer cell tries to compensate for the lack of all these things missing in the blood after fasting. It may be trying to replace them, but it can’t.”
Video interviews with scientists on fasting
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Extended fasting – scientific research
Fasting – Molecular Mechanisms and Clinical Applications:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946160/
Diet, nutrients, phytochemicals, and cancer metastasis suppressor genes. Epigenetic regulation of metastasis suppressor:
wsm.wsu.edu/stories/2014/Fall/2014fall_Meadows_metastasis_metastudy.pdf
Fasting is one of the oldest healing methods:
http://lungcancer.win/fasting-82.html
Fasting for three days can regenerate entire immune system, study finds:
http://www.telegraph.co.uk/science/2016/03/12/fasting-for-three-days-can-regenerate-entire-immune-system-study/
Just as with chemotherapy, fasting slowed the growth and spread of tumors:
https://news.usc.edu/29428/fasting-weakens-cancer-in-mice/
Fasting-like diet turns the immune system against cancer:
http://news.usc.edu/103972/fasting-like-diet-turns-the-immune-system-against-cancer/
Fasting and cancer treatment in humans: A case series report:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/
The role of metabolic therapy in treating glioblastoma multiforme:
https://www.ncbi.nlm.nih.gov/pubmed/25949849
Three-day fasting “safe and feasible” for cancer patients on chemotherapy:
http://www.ncbi.nlm.nih.gov/pubmed/25949849
Cancer as a metabolic disease: implications for novel therapeutics:
http://www.ncbi.nlm.nih.gov/pubmed/24343361
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865572/
Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy:
http://stm.sciencemag.org/content/4/124/124ra27.short
2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting: https://www.ncbi.nlm.nih.gov/pubmed/21439033?dopt=Abstract
21-day water-only fast after which enlarged lymph nodes were substantially reduced in size (Follicular lymphoma (FL), the second most common non-Hodgkin’s lymphoma (NHL)):
http://casereports.bmj.com/content/2015/bcr-2015-211582.abstract
Intermittent fasting – scientific research
Short-term fasting induces profound neuronal autophagy:
https://www.ncbi.nlm.nih.gov/pubmed/20534972
Intermittent fasting in breast cancer risk and survivorship. Insight from the women’s healthy eating and living study: http://cancerres.aacrjournals.org/content/76/4_Supplement/P3-09-01.abstract
The manner in which calories are restricted impacts mammary tumor cancer prevention: http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2011;volume=10;issue=1;spage=21;epage=21;aulast=Cleary
The Benefits of a Ketogenic Diet and Its Role in Cancer Treatment: http://articles.mercola.com/sites/articles/archive/2013/06/16/ketogenic-diet-benefits.aspx
The Ketogenic Diet For Cancer – Any Good?
http://marnieclark.com/the-ketogenic-diet-for-cancer-any-good/
Fasting and Cancer: Has Nature Provided a Treatment All Along?
http://www.cavemandoctor.com/2015/02/26/fasting-cancer-nature-provided-treatment-along/
Alternate-day fasting and chronic disease prevention: a review of human and animal trials: https://www.ncbi.nlm.nih.gov/pubmed/17616757
Episode 1: Breast Cancer and Fasting – The Big JAMA Article
http://colinchamp.com/episode-1-breast-cancer-fasting-big-jama-article/
The Roles of Intermittent Fasting and Carbohydrates in Cancer Therapy’ – Dawn Lemanne, MD, MPH: https://www.youtube.com/watch?v=uG3lUgIvBZM
Healing Cancer on Time – How intermittent fasting may help:
http://www.hope4cancer.com/information/healing-cancer-on-time-how-intermittent-fasting-may-help.html
Documentaries on fasting
Norwegian documentary about fasting:
https://www.youtube.com/watch?v=kH9GT-IrFQ4&feature=youtu.be&ab_channel=vidzfromherebedragons
BBC documentary about fasting:
https://goo.gl/xGN68o
Debunking myths on fasting – other blogs
About muscle loss myth during fasting:
http://www.leangains.com/2010/10/top-ten-fasting-myths-debunked.html
How Intermittent Fasting Stacks Up Among Obesity-Related Myths, Assumptions, and Evidence-Backed Facts: http://fitness.mercola.com/sites/fitness/archive/2013/03/01/daily-intermittent-fasting.aspx
A detailed, up-to-date 7,000 word guide on 15 health benefits of intermittent fasting according to science, and includes carefully-researched suggested meal plans: https://www.jenreviews.com/intermittent-fasting/